ABSTRACT
Objective To study the clinical characteristics and relative risk factors of hypertensive inpatients aged over 80 years.Methods From February 2003 to May 2012,336 hypertensive inpatients aged over 80 years were enrolled in the study.Medical history and family history including height,weight,blood pressure,fasting glucose,total cholesterol,triglyceride,high-density lipoprotein cholesterol,low-density lipoprotein cholesterol,creatinine,urea nitrogen,uric acid and urine protein levels were recorded and analyzed statistically.Results The elderly hypertensive inpatients over 80 years old had systolic hypertension with widening pulse pressure and the decline in glomerular filtration rate.The incidence of dyslipidemia,atrial fibrillation,microalbuminuria,coronary heart disease,cerebrovascular disease were 56.5 ％ (190/336),13.4 ％(45/336),15.8％ (53/336),41.4％ (139/336) and 24.1％ (81/336),respectively.Whereas there was no significant sex difference (P＞0.05).A significant difference was found in the incidence of left vetricular hypertrophy between males (10.4％,25/240) and females (22.9％,22/96) (x2 =8.91,P＜0.01).The prevalence of diabetes in males (46.3％,111/240) was significantly higher than in females (28.1％,27/96) (x2=9.38,P＜0.01).From the 336 patients in the study,311 (92.6％)were treated by antihypertensive agents.The antihypertensive drugs included diuretics (37 patients,11.9％),calcium channel blocker (182 patients,58.5％),angiotensin receptor antagonists (89 patients,28.6％),angiotensin converting enzyme inhibitors (68 patients,21.9％),β-blockers (92 patients,29.6％),α-blockers (31 patients,10.0％),either alone (109 patients,35.0％) or in combination (202 patients,65.0％).96 (30.9％) patients were medically treated for dyslipidemia (drugs including statins).151 (48.6％) patients were treated with antiplatelet drugs.Conclusions The elderly hypertensive inpatients,over 80 years old,were accompanied by multiple risk factors and target organ damage,and most of them was treated with antihypertensive agents in combination.